Fungistin 12 ml

$22.00

Nystatin inhibits the growth of a wide range of pathogenic and nonpathogenic yeasts and fungi, including Candida albicans. Nystatin works against fungi by binding to sterols in the cell membrane of the fungus. The membrane loses its ability to operate as a selective barrier as a result of binding, and potassium and other cellular contents are lost. It has a low absorption rate in the gastrointestinal tract.

Nystatin inhibits the growth of a wide range of pathogenic and nonpathogenic yeasts and fungi, including Candida albicans. Nystatin works against fungi by binding to sterols in the cell membrane of the fungus. The membrane loses its ability to operate as a selective barrier as a result of binding, and potassium and other cellular contents are lost. It has a low absorption rate in the gastrointestinal tract.

Administration & Dosage

Children:

  • In intestinal and oral candidiasis (thrush): 1,00,000 units (1 ml) should be dropped into the mouth four times daily.The longer the suspension is kept in contact with the affected area in the mouth, before swallowing, the greater will be its effect.

  • For prophylaxis in the newborn: The suggested dose is 1,00,000 units (1 ml) once daily or as prescribed by the physician.

Adult:

  • For the treatment of intestinal or esophageal candidiasis: 5,00,000 units (5 ml) by mouth 3 or 4 times daily. The dose may be doubled, if required.

  • For prophylaxis of intestinal candidiasis in adults: 10,00,000 units (10 ml) daily.

  • For prophylaxis to suppress the over growth of Candida albicans in patients receiving broad spectrum antibiotic therapy: 10,00,000 units (10 ml) daily.

  • For the treatment of dental sores and oral infection: 1,00,000 units (1 ml) suspension should be dropped into the mouth four times daily.

Elderly: Older people with intestinal candidiasis who are unable to swallow tablets should be given 5,00,000 units (5 ml) suspension four times daily.

 

Contraindications

There are no known contraindication to the use of Nystatin except hypersensitivity to the drug.

 

Side Effects

Nausea, vomiting and diarrhoea have occasionally been reported with doses of Nystatin exceeding 4 to 5 million units daily. No systemic effects or allergic reactions have been associated with its oral use. 

 

Pregnancy & Lactation

Pregnancy category C: Mouth/Throat/PO/Topical
Pregnancy category A: Vaginal

 

Precautions & Warnings

Because absorption from the gastrointestinal tract is minimal, no extra precautions are required during pregnancy or lactation.

 

Therapeutic Class

Drugs for subcutaneous and mycoses, Drugs used in Vaginal and Vulval condition.

 

Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.