Xylovin 0.05% 10 ml

$87.00

Nasal congestion is caused by various causes, such as sinusitis and allergic or non-allergic rhinitis, which can cause congestion of the venous sinuses that line the nasal mucosa. Activation of alpha-adrenergic receptors leads to nasal mucosal vasoconstriction and restoration of nasal airflow. Since they are most abundantly expressed in human nasal mucosa, α1A and α2B adrenergic receptors may play the most important role in the vasoconstriction of human nasal mucosa. Xylometazoline is a more selective α2B adrenergic receptor agonist with affinity for α1A, α2A, α2C, α1B and α1D adrenergic receptors. Xylometazoline reduces nasal resistance during inhalation and exhalation, and increases the volume of nasal airflow. Compared to oxymetazoline (another imidazoline nasal decongestant), ximetazoline has a slightly faster onset of action, although its duration of action is similar. In one study, subjects with nasal congestion reported that in addition to nasal congestion, earache and sore throat were also relieved: oxymetazoline is hypothesized to mediate vasoconstriction of the nasal mucosa containing the sinuses With this effect, nasal congestion can breathe through the nose. , relieving sore throat caused by dryness and irritation of the throat caused by mouth breathing.

Nasal congestion is caused by various causes, such as sinusitis and allergic or non-allergic rhinitis, which can cause congestion of the venous sinuses that line the nasal mucosa. Activation of alpha-adrenergic receptors leads to nasal mucosal vasoconstriction and restoration of nasal airflow. Since they are most abundantly expressed in human nasal mucosa, α1A and α2B adrenergic receptors may play the most important role in the vasoconstriction of human nasal mucosa. Xylometazoline is a more selective α2B adrenergic receptor agonist with affinity for α1A, α2A, α2C, α1B and α1D adrenergic receptors. Xylometazoline reduces nasal resistance during inhalation and exhalation, and increases the volume of nasal airflow. Compared to oxymetazoline (another imidazoline nasal decongestant), ximetazoline has a slightly faster onset of action, although its duration of action is similar. In one study, subjects with nasal congestion reported that in addition to nasal congestion, earache and sore throat were also relieved: oxymetazoline is hypothesized to mediate vasoconstriction of the nasal mucosa containing the sinuses With this effect, nasal congestion can breathe through the nose. , relieving sore throat caused by dryness and irritation of the throat caused by mouth breathing.

Dosage & Administration

Adults: Xylometazoline 0.1%: 2 or 3 drops in each nostril two to three times daily. Xylometazoline 0.1% should not be used for children under the age of 12 years. Children 6 to 12 years of age: Xylometazoline 0.05%: 2 or 3 drops in each nostril two or three times daily. Children less than 6 years of age: Xylometazoline 0.05%: 1 drop in each nostril two or three times daily. Infants less than 3 months: Not to be used in infants less than 3 months.

 

Interaction

There have been no documented medication interactions.

 

Contraindications

Xylose oxazoline nasal drops should not be used in patients undergoing transsphenoidal hypophysectomy or exposure of the dura mater. It is also contraindicated in patients allergic to trichoderma. Each xylazoline nasal drop can only be used by one person to prevent any cross infection. Patients are advised not to take decongestants continuously for more than 7 days.

 

Side Effects

The following adverse effects have been reported on occasion:

  • In the nose and throat, there is a burning sensation.

  • Irritation on the spot

  • Nausea and nasal mucosa that is dry.

 

Pregnancy & Lactation

Pregnancy Category C. Xerozoline should not be used during pregnancy. The use of Otrivin during breastfeeding should only be done under the supervision of a doctor.

 

Precautions & Warnings

Children under the age of 12 should not be given Xylometazoline Hydrochloride nasal drops (0.1 percent). In situations of chronic rhinitis, drops should not be administered for an extended period of time. Use of the drops for an extended period of time may result in rebound congestion and drug-induced rhinitis.

 

Therapeutic Class

Nasal Anti-histamine preparations.

 

Storage Conditions

Protect yourself from the sun. Do not use the bottle for more than 28 days after opening it for hygiene concerns.